Sahin-Toth, M. : rechercher sur Z-Library

Année:

2004

Langue:

english

Fichier:

PDF, 223 KB

english, 2004

Hereditary pancreatitis caused by a three amino-acid insertion within the activation peptide of human cationic trypsinogen (PRSS1)

Geisz, A., Joergensen, M.T., Brusgaard, K., Schaffalitzky de Muckadell, O.B., Gerdes, A.-M., Hegyi, P., Sahin-Tóth, M.

Journal:

Nemeth, B. C., Sahin-Toth, M.

Année:

2012

Langue:

english

Fichier:

PDF, 42 KB

english, 2012

Human cationic trypsinogen (PRSS1) variants and chronic pancreatitis

Journal:

AJP Gastrointestinal and Liver Physiology

Année:

2014

Langue:

english

Fichier:

PDF, 490 KB

english, 2014

Gene conversion cetween functional trypsinogen genes PRSS1 and PRSS2 associated with chronic pancreatitis in a six-year-old girl

Niels Teich, Zsófia Nemoda, Henrik Köhler, Wolfram Heinritz, Joachim Mössner, Volker Keim, Miklós Sahin-Tóth

Journal:

Niels Teich, Jonas Rosendahl, Miklós Tóth, Joachim Mössner, Miklós Sahin-Tóth

Année:

2005

Langue:

english

Fichier:

PDF, 149 KB

english, 2005

Mutations of human cationic trypsinogen (PRSS1) and chronic pancreatitis

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 208 KB

english, 2006

Signal peptide variants that impair secretion of pancreatic secretory trypsin inhibitor (SPINK1) cause autosomal dominant hereditary pancreatitis

Orsolya Király, Arnaud Boulling, Heiko Witt, Cédric Le Maréchal, Jian-Min Chen, Jonas Rosendahl, Cinzia Battaggia, Thomas Wartmann, Miklós Sahin-Tóth, Claude Férec

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 413 KB

english, 2007

Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism

Éva Kereszturi, Richárd Szmola, Zoltán Kukor, Peter Simon, Frank Ulrich Weiss, Markus M. Lerch, Miklós Sahin-Tóth

Journal:

Zoltán Kukor, Miklós Tóth, Miklós Sahin-Tóth

Année:

2009

Langue:

english

Fichier:

PDF, 269 KB

english, 2009

Human anionic trypsinogen : Properties of autocatalytic activation and degradation and implications in pancreatic diseases

Journal:

Miklós Sahin-Tóth, H. Ronald Kaback

Année:

2003

Langue:

english

Fichier:

PDF, 706 KB

english, 2003

Cysteine scanning mutagenesis of putative transmembrane helices IX and X in the lactose permease of Escherichia coli

Journal:

Protein Science

Année:

1993

Langue:

english

Fichier:

PDF, 2.88 MB

english, 1993

Cysteine scanning mutagenesis of the N-terminal 32 amino acid residues in the lactose permease of Escherichia coli

Miklós Sahin-Tóth, Bengt Persson, Jeremy Schwieger, Pejman Cohan, H.Ronald Kaback

Journal:

Protein Science

Année:

1994

Langue:

english

Fichier:

PDF, 2.65 MB

english, 1994

The role of transmembrane domain III in the lactose permease of escherichia coli

Miklós Sahin-Tóth, Stathis Frillingos, Eitan Bibi, Alberto Gonzalez, H. Ronald Kaback

Journal:

Protein Science

Année:

1994

Langue:

english

Fichier:

PDF, 1.75 MB

english, 1994

Expression of the murine wild-type tyrosinase gene in transgenic rabbits

Bernhard Aigner, Urban Besenfelder, Janos Seregi, Laszlo V. Frenyo, Tibor Sahin-Toth, Gottfried Brem

Journal:

Transgenic Research

Année:

1996

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1996

Chymotrypsin C mutations in chronic pancreatitis

Jiayi Zhou, Miklós Sahin-Tóth

Journal:

Journal of Gastroenterology and Hepatology

Année:

2011

Langue:

english

Fichier:

PDF, 380 KB

english, 2011

Mesotrypsin, a brain trypsin, activates selectively proteinase-activated receptor-1, but not proteinase-activated receptor-2, in rat astrocytes

Yingfei Wang, Weibo Luo, Thomas Wartmann, Walter Halangk, Miklós Sahin-Tóth, Georg Reiser

Journal:

Journal of Neurochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 439 KB

english, 2006

Human mesotrypsin exhibits restricted S1′ subsite specificity with a strong preference for small polar side chains

Edit Szepessy, Miklós Sahin-Tóth

Journal:

Miklós Sahin-Tóth, Zoltán Kukor, Zsófia Nemoda

Année:

2006

Langue:

english

Fichier:

PDF, 986 KB

english, 2006

Human cationic trypsinogen is sulfated on Tyr154

Journal:

Melinda Bence, Miklós Sahin-Tóth

Année:

2006

Langue:

english

Fichier:

PDF, 483 KB

english, 2006

Asparagine-linked glycosylation of human chymotrypsin C is required for folding and secretion but not for enzyme activity

Journal:

Zoryana Grishina, Ewa Ostrowska, Walter Halangk, Miklós Sahin-Tóth, Georg Reiser

Année:

2011

Langue:

english

Fichier:

PDF, 393 KB

english, 2011

A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis

Witt, Heiko, Sahin-Tóth, Miklós, Landt, Olfert, Chen, Jian-Min, Kähne, Thilo, Drenth, Joost PH, Kukor, Zoltán, Szepessy, Edit, Halangk, Walter, Dahm, Stefan

Journal:

Nature Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 297 KB

english, 2006

Activity of recombinant trypsin isoforms on human proteinase-activated receptors (PAR): mesotrypsin cannot activate epithelial PAR-1, -2, but weakly activates brain PAR-1

Journal:

British Journal of Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 194 KB

english, 2005

Activation and dimerization of type III nitric oxide synthase by submicromolar concentrations of tetra hydrobiopterin in microsomal preparations from human primordial placenta

M. Tóth, Z. Kukor, M. Sahin-Tóth

Journal:

Placenta

Année:

1997

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1997

Trypsinogen Stabilization by Mutation Arg117→His: A Unifying Pathomechanism for Hereditary Pancreatitis?

Miklós Sahin-Tóth, László Gráf, Miklós Tóth

Journal:

Biochemical and Biophysical Research Communications

Année:

1999

Langue:

english

Fichier:

PDF, 116 KB

english, 1999

High-Affinity Ca2+ Binding Inhibits Autoactivation of Rat Trypsinogen

Miklós Sahin-Tóth, Miklós Tóth

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 112 KB

english, 2000

Gain-of-Function Mutations Associated with Hereditary Pancreatitis Enhance Autoactivation of Human Cationic Trypsinogen

Miklós Sahin-Tóth, Miklós Tóth

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 57 KB

english, 2000

Affinity Purification of Recombinant Trypsinogen Using Immobilized Ecotin

Zsolt Lengyel, Gábor Pál, Miklós Sahin-Tóth

Journal:

Protein Expression and Purification

Année:

1998

Langue:

english

Fichier:

PDF, 536 KB

english, 1998

Transport properties and inhibitor sensitivity of isolated and reconstituted porin differ from those of intact mitochondria

György Báthori, Miklós Sahin-Tóth, Attila Fonyó, Erzsébet Ligeti

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1993

Langue:

english

Fichier:

PDF, 833 KB

english, 1993

Expression of human cationic trypsinogen with an authentic N terminus using intein-mediated splicing in aminopeptidase P deficient Escherichia coli

Orsolya Király, Lan Guan, Edit Szepessy, Miklós Tóth, Zoltán Kukor, Miklós Sahin-Tóth

Journal:

Protein Expression and Purification

Année:

2006

Langue:

english

Fichier:

PDF, 239 KB

english, 2006

The kamikaze approach to membrane transport

Kaback, H. Ronald, Sahin-Tóth, Miklós, Weinglass, Adam B.

Journal:

Nature Reviews Molecular Cell Biology

Année:

2001

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2001

67 Genetic Defects in the Trypsin Degrading Enzyme Chymotrypsin C (CTRC) Are Associated with Chronic Pancreatitis

Jonas Rosendahl, Heiko Witt, Richard Szmola, Niels Teich, Miklós Sahin-Tóth

Journal:

Walter Halangk, Milada Butueva, Markus M. Lerch, Miklós Sahin-Tóth, Thomas Wartmann

Année:

2008

Langue:

english

Fichier:

PDF, 87 KB

english, 2008

891 Trypsin Activity in the Mouse Pancreas After Supramaximal Caerulein Stimulation Represents An Inhibitor-Insensitive Isoform

Journal:

Szabó, András, Sahin-Tóth, Miklós

Année:

2008

Langue:

english

Fichier:

PDF, 89 KB

english, 2008

Determinants of chymotrypsin C cleavage specificity in the calcium-binding loop of human cationic trypsinogen

Journal:

Sahin-Tóth, Miklós, Lengyel, Zsolt, Tsunekawa, Hiroshi

Année:

2012

Langue:

english

Fichier:

PDF, 565 KB

english, 2012

Cloning, sequencing, and expression of cscA invertase from Escherichia coli B-62

Journal:

Canadian Journal of Microbiology

Année:

1999

Fichier:

PDF, 166 KB

1999

Helix Packing in the Sucrose Permease of Escherichia coli: Properties of Engineered Charge Pairs between Helixes VII and XI

Frillingos, Stathis, Sahin-Toth, Miklos, Lengeler, Joseph W., Kaback, H. Ronald

Journal:

Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 1.82 MB

english, 1995

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk

Beer, S., Zhou, J., Szabo, A., Keiles, S., Chandak, G. R., Witt, H., Sahin-Toth, M.

Journal:

Gut

Année:

2013

Langue:

english

Fichier:

PDF, 2.19 MB

english, 2013

Robust autoactivation, chymotrypsin C independence and diminished secretion define a subset of hereditary pancreatitis-associated cationic trypsinogen mutants

Geisz, Andrea, Hegyi, Péter, Sahin-Tóth, Miklós

Journal:

Rónai, Zsolt, Witt, Heiko, Rickards, Olga, Destro-Bisol, Giovanni, Bradbury, Andrew R. M., Sahin-Tóth, Miklós

Année:

2013

Langue:

english

Fichier:

PDF, 610 KB

english, 2013

A common African polymorphism abolishes tyrosine sulfation of human anionic trypsinogen (PRSS2)

Journal:

Biochemical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 640 KB

english, 2009

Cathepsin L in the pancreatic secretory pathway and its effect on disease-relevant trypsinogen mutants

Halangk, Walter, Kukor, Zoltan, Mayerle, Julia, Ruthenbuerger, Manuel, Sahin-Toth, Miklos, Lerch, Markus M.

Journal:

Nemoda, Zsófia, Teich, Niels, Hugenberg, Christin, Sahin-Tóth, Miklós

Année:

2003

Langue:

english

Fichier:

PDF, 246 KB

english, 2003

Genetic and biochemical characterization of the E32del polymorphism in human mesotrypsinogen

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 139 KB

english, 2005

Characterization of human chymotrypsinogen activation

Geisz, A., Szabó, A., Hegyi, P., Rakonczay, Z., Széll, M., Sahin-Tóth, M.

Journal:

Endocrinology and Metabolism Clinics of North America

Année:

2012

Langue:

english

Fichier:

PDF, 42 KB

english, 2012

Biochemical Models of Hereditary Pancreatitis

Sahin-Tóth, Miklós

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 132 KB

english, 2006

M1865 Hereditary Pancreatitis Caused by Intragenic Duplication Affecting the Activation Peptide of Human Cationic Trypsinogen (PRSS1)

Joergensen, Maiken T., Geisz, Andrea, Brusgaard, Klaus, de Muckadell, Ove B. Schaffalitzky, Gerdes, Anne-Marie, Hegyi, Péter, Sahin-Toth, Miklos

Journal:

Németh, B., Sahin-Tóth, M.

Année:

2010

Langue:

english

Fichier:

PDF, 47 KB

english, 2010

Autoactivation of mouse trypsinogens and regulation by chymotrypsins

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 41 KB

english, 2013

Role of cathepsin L in proteolytic cleavage of SPINK1

Halangk, W., Wartmann, T., Behn, C.-O., Günther, A., Sahin-Toth, M., Rosendahl, J., Herms, M., Mayerle, J., Lerch, M.M., Weiss, F.U.

Journal:

Beer, Sebastian, Sahin-Tóth, Miklós

Année:

2013

Langue:

english

Fichier:

PDF, 44 KB

english, 2013

Defective mRNA splicing caused by exonic CTRC and SPINK1 variants

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 47 KB

english, 2013

Rare cationic trypsinogen mutations found in subject with pancreatitis are neutral variants or may even be protective

Schnúr, A., Hegyi, P., Sahin-Tóth, M.

Journal:

Nemeth, Balazs, Sahin-Toth, Miklos

Année:

2012

Langue:

english

Fichier:

PDF, 59 KB

english, 2012

882 Biochemical Characterization of Mouse Trypsinogens

Journal:

Halangk, Walter, Wartmann, Thomas, Sahin-Tóth, Miklos, Nowack, Björn, Mayerle, Julia, Lerch, Markus M.

Année:

2013

Langue:

english

Fichier:

PDF, 312 KB

english, 2013

Preferential cleavage by cathepsin L of N34S-SPINK1 in comparison to the wild-type inhibitor

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 54 KB

english, 2013

Pancreatitis associated chymotrypsin C (CTRC) mutations show distinct loss-of-function phenotypes

Beer, S., Zhou, J., Szabó, A., Keiles, S., Chandak, G.R., Witt, H., Sahin-Tóth, M.

Journal:

Halangk, Walter, Wartmann, Thomas, Lippert, Hans, Sahin-Toth, Miklos, Lerch, Markus M.

Année:

2012

Langue:

english

Fichier:

PDF, 43 KB

english, 2012

Hereditary pancreatis is not caused by altered trypsin inhibitor affinity to mutant trypsin

Journal:

Geisz, Andrea, Hegyi, Peter, Rakonczay, Zoltan, Czakó, László, Sahin-Tóth, Miklós

Année:

2003

Langue:

english

Fichier:

PDF, 246 KB

english, 2003

Mutations of the trypsinogen activation peptide in hereditary pancreatitis

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 54 KB

english, 2013

Gene conversion between cationic trypsinogen (PRSS1) and the pseudogene trypsinogen 6 (PRSS3P2) in a patient with chronic pancreatitis

Beer, S., Weiss, F.-U., Simon, P., Lerch, M.M., Sahin-Tóth, M.

Journal: